| Pair Name | Beta-Elemene, Cabazitaxel | ||
| Phytochemical Name | Beta-Elemene (PubChem CID: 6918391 ) | ||
| Anticancer drug Name | Cabazitaxel (PubChem CID: 9854073 ) | ||
| Structure of Phytochemical |
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3D
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| Structure of Anticancer Drug |
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| Pair Name | Beta-Elemene, Cabazitaxel | |||
| Disease Info | [ICD-11: 2A00] | Glioblastoma multiforme | Investigative | |
| Gene Regulation | Up-regulation | Expression | ATP1A1 | hsa476 |
| In Vitro Model | RG2 | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_1092 |
| In Vivo Model | Approximately 2.5×10⁷ glioma-luc cells in medium were injected slowly into the brain right striatum of nude mice (bright lateral: 2.0 mm, bregma: 1.8 mm, depth: 3.5 mm). | |||
| Result | These findings indicate that the active-targeting biomimetic liposome, Tf-ELE/CTX@BLIP, is a promising nanoplatform for delivery of drugs to gliomas. | |||
| No. | Title | Href |
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| 1 | Active targeting of orthotopic glioma using biomimetic liposomes co-loaded elemene and cabazitaxel modified by transferritin. J Nanobiotechnology. 2021 Sep 26;19(1):289. doi: 10.1186/s12951-021-01048-3. | Click |
